Charlotte FC (8-9-1, eighth in the Eastern Conference) vs. Sporting Kansas City (4-10-4, 14th in the Western Conference)

New York Red Bulls (8-7-3, seventh in the Eastern Conference) vs. Toronto FC (3-10-4, 13th in the Eastern Conference)

Philadelphia Union (11-3-4, first in the Eastern Conference) vs. Chicago Fire (7-6-4, eighth in the Eastern Conference)

Atlanta United FC (4-9-5, 12th in the Eastern Conference) vs. Columbus Crew (8-3-7, third in the Eastern Conference)

Orlando City SC (8-4-6, fourth in the Eastern Conference) vs. Saint Louis City SC (3-9-6, 15th in the Western Conference)

Nashville SC (9-4-5, third in the Western Conference) vs. New England Revolution (6-5-5, 10th in the Eastern Conference)

FC Cincinnati (10-5-3, second in the Eastern Conference) vs. CF Montreal (2-11-5, 14th in the Eastern Conference)

New York Liberty (10-3, 7-1 Eastern Conference) at Golden State Valkyries (7-6, 4-4 Western Conference)

Connecticut Sun (2-12, 2-6 Eastern Conference) at Las Vegas Aces (6-7, 3-6 Western Conference)

Indiana Fever (6-7, 6-5 Eastern Conference) at Seattle Storm (9-5, 8-4 Western Conference)